Author(s): Hashem HA and Yasser Hamed Mustafa
MCI (Mild cognitive impairment) is an intermediate stage in the trajectory from normal cognition to dementia. Subjects with MCI have a high rate of progression to dementia over a relatively short period. Subjects with MCI also experience a greater mortality than cognitively normal subjects.
Method: One hundred and fifty eight patients aged 65 years or more (106 males and 52 females) were included in our study. In addition to a detailed medical and neurological history and examination, MMSE (Mini-Mental State Examination), CDR (Clinical Dementia Rating Scale), Geriatric Depression Scale, Global Deterioration Scale and lipid profile were performed for all patients.
Results: Significant correlation between metabolic syndrome and its components and MCI.
Conclusion: Patients with metabolic syndrome have higher risk for development of MCI.